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Machine learning and systems genomics approaches for multi-omics data.

In light of recent advances in biomedical computing, big data science, and precision medicine, there is a mammoth demand for establishing algorithms in machine learning and systems genomics (MLSG), together with multi-omics data, to weigh probable phenotype-genotype relationships. Software frameworks in MLSG are extensively employed to analyze hundreds of thousands of multi-omics data by high-throughput technologies. In this study, we reviewed the MLSG software frameworks and future directions with respect to multi-omics data analysis and integration. Our review was targeted at researching recent approaches and technical solutions for the MLSG software frameworks using multi-omics platforms.

Machine learning and systems genomics approaches for multi-omics data.

> 商业许可源文 · EUROPE_PMC · [CC-BY](https://creativecommons.org/licenses/by/)

书目信息

  • 引用:Lin E, Lane HY. (2017). Machine learning and systems genomics approaches for multi-omics data. Biomarker research. PMID 28127429 · PMC5251341 · DOI 10.1186/s40364-017-0082-y
  • 证据类型:REVIEW
  • 主题:multi-omics、clinical-genomics
  • 被引次数(采集时):95
  • 原始记录:[Europe PMC](https://europepmc.org/article/MED/28127429)
  • 来源许可:[CC-BY](https://creativecommons.org/licenses/by/)
  • 作者摘要(按来源许可复用)

    In light of recent advances in biomedical computing, big data science, and precision medicine, there is a mammoth demand for establishing algorithms in machine learning and systems genomics (MLSG), together with multi-omics data, to weigh probable phenotype-genotype relationships. Software frameworks in MLSG are extensively employed to analyze hundreds of thousands of multi-omics data by high-throughput technologies. In this study, we reviewed the MLSG software frameworks and future directions with respect to multi-omics data analysis and integration. Our review was targeted at researching recent approaches and technical solutions for the MLSG software frameworks using multi-omics platforms.

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    Machine learning and systems genomics approaches for multi-omics data. · GeniOmics